After a 12-hour fast and 24-hour abstinence from exercise and smoking, antecubital blood was collected in EDTA, centrifuged, and frozen at −80°C until analysis. Plasma CRP concentrations were measured with the Dade-Behring high-sensitivity immunoassay (detection range=0 to 6.5 mg/dL).1,2 Additional CHD risk factor concentrations were obtained with standard automated assay procedures described elsewhere.11,13,1